It has been reported that Brazil have requested that FIFA invoke the five-day rule, which means at least eight Premier League players will not be available for selection this weekend.
The affected clubs are Manchester City, Leeds, Liverpool, Chelsea and Manchester United.
Liverpool will be without Becker Alisson, Roberto Firmino and Fabinho, for their trip to Leeds on Sunday.
Marcelo Bielsa’s squad will also not include Raphinha.
Manchester City duo of Gabriel Jesus and Ederson will miss their clash with Leicester City on Saturday.
Chelsea’s Thiago Silva and Manchester United’s Fred are also affected.
The Premier League clubs had risked FIFA ban, after expressing issues with the players travelling for international duty amid the UK’s strict COVID-19 regulations.
Those who arrive in the UK from red list countries are required to spend 10 days in isolation.